Diagnostic value of stringed esophageal capsule endoscopy for the esophageal diseases

Abstract

Objective To investigate the diagnostic value of the modified esophageal capsule endos- copy （stringed esophageal capsule endoscopy, SCE） for esophageal diseases. Methods A total of 80 pa- tients with esophageal related symptoms underwent SCE followed by esophagogastroduodenoscopy （EGD）. The examination time, detection rate of esophageal lesions, complications and adverse effects were compared. Results All patients completed the study. The mean examination time of SCE and EGD was 226. 18 ＋ 110. 30 seconds and 21.28 ＋8.01 seconds respectively （t = - 16. 665, P =0. 000）. A total of 119 lesions were detected by SCE and EGD, and the diagnostic accordance rate of SCE and EGD was 82.4% （98/119）. Ten lesions of advanced squamous carcinoma, 5 lesions of high grade intraepithelial neoplasia and 3 lesions of early squamous carcinoma were detected by both examinations, all of which were confirmed by histopatho- logic examination. The overall rate of complication in SCE （ 1.3%, 1/80） was significantly lower than that of EGD （8.8%, 7/80, X2 = 4. 238, P = 0. 040） and the rates of swallow difficulty （ P = 0. 022）, throat dis- comfort （ P = 0. 007） and vomiting （ P = 0. 000） of SCE were significantly lower than those of EGD. Con- clusion SCE is a feasible, easy-to-operate, safe, well tolerated and accurate method for detection of esopha- geal diseases, and could be a non-invasive alternative for conventional EGD. Key words: Esophagus ; Diagnosis; Capsule endoscopy; String