Diagnostic value of red blood cell distribution width in patients with organophosphate poisoning in emergency department of Sina hospital in 2019

Abstract

Introduction: Organophosphates are pesticides used for agricultural purposes, and their poisoning has critical complications. The purpose of this study was to determine the estimated Red Blood cell distribution width (RDW) prognostic role in patients with organophosphate poisoning in the emergency department. Materials and methods: In this Descriptive-analytical study, patients with acute organophosphate poisoning referred to the emergency department of Sina Hospital in Tabriz from March 2019 to March 2020 were enrolled. The primary outcome of the patients including, organophosphate-induced RDW changes, and the secondary outcome including, organophosphate-induced death were recorded. Results: Eighty two patients with organophosphate poisoning were enrolled in this study. The mean age was 36.21 years. Of 82 patients, insecticidal poisoning, herbicide, fungicides, and acaricide were seen in 62 (76.8%), 16 (19.5%), 1 (1.2%), and 1 (1.2%) patients respectively. There were no statistically significant difference observed between types of pesticides and patients’ outcomes (p> 0.05). There was no statistically significant difference between different organophosphates in terms of pH, HCO3 , PCO2 , WBC, Hb, platelets, RDW, sodium, potassium, PT, PTT, INR, urea, creatinine, and cholinesterase (p> 0.05). Conclusion: Generally, RDW in patients with organophosphates toxicity does not have prognostic value and is not affected by the severity of poisoning.