Abstract
Objective To evaluate the clinical significance of multiparametric-MRI(mpMRI) in the prediction of T stage in bladder cancer and predicting muscle invasive bladder carcinomas. Methods From March 2015 to March 2017, 75 patients with bladder cancer were retrospectively reviewed with high-resolution T2-weighted images (HR-T2WI), diffusion weighted imaging (DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and other the clinical data such as ADC of muscular layer in normal and carcinomas bladder. The accuracy of these techniques was used to diagnose the T stage, and the ROC curve was used to analyze the ability of ADC to diagnose muscle invasive bladder carcinomas. Results The accuracy of the mpMRI (88.00%)was superior to DWI (76.00%), DCE-MRI (66.67%) and HR-T2WI (66.67%) in differentiating non-muscle invasive from muscle invasive. The agreement between the mpMRI and histopathological staging (kappa=0.816) were also best. The ROC curve of muscle invasive bladder carcinomas was 0.983 (P=0.01). Conclusions The mpMRI is an effective tool for determining local T stages and muscle invasive bladder carcinomas. Key words: Urinary Bladder Neoplasms; Magnetic Resonance Spectroscopy
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