Abstract

Automated urine analysis poses the advantage of rapid turn around time and is suitable for initial screening of large number of samples.However, standardized manual microscopic examination of urine sediment remains valuable for a variety of differential diagnosis,such as screening the potential causes of hematuria, to predict proliferative and non-proliferative renal pathological injury. Urinary sediment scoring system is often used to differentiate acute tubular necrosis (ATN) from pre-renal acute kidney injury (AKI).The urinary podocytes serves as a marker of glomerular injury to determine the location of and to monitor activity of glomerular lesions, as well as to differentiate focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD).These useful analyses shows the importance of urine microscopy in the clinical practice of nephrology.(Chin J Lab Med, 2012,35:780-783) Key words: Kidney diseases; Kidney failure; acute; Podocytes; Urinalysis; Urine sediment; Microscopy

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