Diagnostic value of endoscopic ultrasonography for ulcerative colitis

Abstract

Objective To study the consistency and complementarity of endoscopic ultrasonography （EUS） , white light endoscopy （WLE） and magnifying endoscopy （ME） in diagnosis of ulcerative colitis （UC）. Methods We collected 125 cases of UC patients diagnosed by WLE and EUS （including 51 cases of WLE ＋ ME ＋ EUS）. According to UC mucosal morphology under WLE and crypt openings under ME, we divided all the cases into several groups and analyzed intestinal wall thickness （TWT） under EUS in each group. Results According to the results of UC inflammation degree under WLE, all patients were divided into four groups： 16 severe cases, 46 moderate cases, 44 mild, and 19 remission stage. TWT results were （5. 903 ±1.551 ） ram, （4. 673 ± 1. 235 ） mm, （3. 756 ± 1. 322 ） mm and （ 3. 464 ± 0.970） mm, respective- ly. Differences were significant between any two groups （ P 〈 0. 05 ）, except for that between mild and remis- sion groups. According to the results of UC inflammation degree under ME, all patients were divided into six groups ： 9 cases of villous-like structure, 9 cases of typical coral reef-like structure, 8 severe coral reef-like structure, 13 regular crypt opening, 6 epithelial minimal defect and 6 small yellow spot （SYS）. TWT results were （5.701 ±0.941）mm, （5.518±0.581）mm, （5. 181 ±0.751）mm, （3.763±0.659）mm, （3.587± 0. 461 ） mm and （ 2. 505 ± 0. 330 ） mm, respectively. Differences were significant between any two groups（ P 〈 0.05 ） except for those betweerl epithelial minimal defect and regular crypt opening, typical c, oral reef- like structure, villous-like and severe eural reef-like structure. FUS results showed SYS （6/6） and regular crypt opening （ 10/13 ） were mostly located in mucosa, while lesions of severe coral reef-like structure （8/8） invaded the museularis propria. Conclusion EUS shows high consistency with WLE and ME in di- agnosis of UC inflammation degree and invasive depth. It could assist and even substitute ME for evaluation. Key words: Colitis,uleeralive; Endoscopic uhrasonography; Magnifying endoscopy