Diagnostic value of endoscopic ultrasonography for large gastric folds

Abstract

Objective To evaluate endoscopic ultrasonography （EUS） for diagnosis of large gastric folds. Methods EUS was performed in 66 patients with possible large gastric folds which could not be diag- nosed by conventional gastroscopy. The characteristics of EUS findings were analyzed, and the EUS results were compared with pathological findings to evaluate the sensitivity, specificity and accuracy of EUS. Re- suits The diagnostic sensitivity, specificity and accuracy of EUS for diffused infiltrated gastric cancer were 92. 3% （24/26）, 95.1% （39/41） and 95.5% （63/66）, respectively, and those for gastric lymphoma were 92. 3% （12/13）, 96. 1% （49/51） and 92. 4% （61/66）, respectively. The accuracy in differential diagno- sis of benign and malignant disease was 93.9% （62/66）. There were statistical differences between benign and malignant large gastric folds in characteristics of EUS findings, including width of gastric wall, enlarge- ment of muscularis propria and preservation of gastric layer （P 〈 0. 05 ）. Conclusion EUS is of high accu- racy for diagnosis of large gastric folds, especially for diffused infiltrated gastric cancer and gastric lympho- ma. Such features as width of gastric wall, the enlargement of muscularis propria and the preservation of gas- tric layer are important features for differential diagnosis of benign and malignant lesions. Key words: Endoscopic ultrasonography; Large gastric folds