Diagnostic value of dynamic electrocardiogram and myocardial enzyme spectrum in patients of acute upper respiratory tract infection complicated with viral myocarditis

Abstract

Objective To investigate the diagnostic value of dynamic electrocardiogram and myocardial zymogram in patients with acute upper respiratory tract infection complicated with viral myocarditis. Methods From January 2012 to June 2017, a total of 123 patients with acute upper respiratory tract infection complicated with viral myocarditis in the Fifth Affiliated Hospital of Xinjiang Medical University were selected as observation group, while 123 patients with acute upper respiratory tract infection without other complications were selected as control group in this hospital. The levels of serum creatine kinase (CK), creatine kinase isoenzyme (CK-MB), aspartate aminotransferase (AST), α-hydroxybutyrate dehydrogenase (α-HBDH) and hydroxybutyric dehydrogenase were dectected, respectively; and the characteristics of dynamic electrocardiogram change of patients were investigated. Results The levels of serum CK and CK-MB of patients in observation group were significantly higher than those of control group (t = 2.887, P= 0.004, t = 8.872,P < 0.001). Since the third day after admission, the serum CK and CK-MB levels of observation group decreased, with significant difference (bothP < 0.001). The detection rate ofⅠdegree atrioventricular block,Ⅱdegree atrioventricular block, T wave changes, QRS low potential and atrial premature beat in observation group were significantly higher than those of conventional electrocardiogram, with significant differences (χ2= 7.899,P= 0.005; χ2= 3.980,P= 0.046;χ2= 10.543,P= 0.001;χ2= 13.934,P < 0.001;χ2= 5.371,P= 0.020). The positive detection rate of dynamic electrocardiogram combined with myocardial zymogram was significantly higher than that of myocardial enzyme spectrum, dynamic electrocardiogram and routine electrocardiogram alone, with significant differences (allP< 0.05). Conclusions Dynamic electrocardiogram combined with myocardial zymogram could improve the diagnostic rate of acute upper respiratory tract infection complicated with viral myocarditis. Key words: Dynamic electrocardiogram; Myocardial enzyme; Upper respiratory tract infection; Viral myocarditis