Abstract
Objective To explore the relationship between the characteristics of dynamic contrast-enhanced MRI (DCE-MRI) and the stages of endometrial cancer. Methods A retrospective analysis of DCE-MRI manifestation in 55 patients with scratch-pathologically confirmed endometrial cancer was performed.All patients were divided into different groups according to differentiation,muscle layer infiltration,cervix involvement and metastasis.The enhanced rate,including the arterial phase relative signal increase ratio (ARSI%),the maximal relative signal increase ratio (MRSI%) and the signal enhancement ratio (SER%),was calculated at different time (i.e.16 s,32 s,48 s,64 s and 300 s),respectively.Time-intensity curves (TIC) of lesions were also obtained and divided into 4 subtypes.Two sample t test was performed to compare the MRSI% among groups,and the Mann-WhitneyUtest was performed in ARSI% and SER% as well. Results The early phase enhanced rate of normal tissue was 894±355,higher than that of tumor 716±215 (t=-2.911,P<0.01).The delayed phase enhanced rate of normal tissue was 1111±289,higher than that of tumor 803±289 (t Key words: Endometrial neoplasms; Magnetic resonance imaging
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