Abstract
Endocytoscopy enables us to observe cellular nucleus in vivo in the squamous esophagus and pharynx. Endocytoscopy is a contact endoscopy with 340-1100-fold magnification. Topical spray of crystal violet and methylene blue solution creates a well-contrasted image which is similar to hematoxylin and eosin staining. Endocytoscopic findings of tissue atypia are summarized in endocytoscopic (EC) classification. EC-1 is nonneoplastic, which includes normal (EC-1a) and inflammatory or reactive (EC-1b). EC-2 is a borderline lesion. EC-3 is a cancerous image, often with increased cellularity and with enlarged and polymorphic nuclei. This article is part of an expert video encyclopedia.
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