Abstract
Background: Tumors of lung are common in Nepal. The risk of malignancy has to be judged prior to surgery for which bronchoscopy is often done. Brocho-alveolar lavage and bronchial biopsy are routine procedure done for diagnosis of lung cancer during bronchoscopy. This study was done to correlate the cytology of broncho-alveolar lavage specimen with histopathology in malignant tumors of the lug in our setup.
 Materials and methods: This study was conducted at department of pathology, Nobel Medical College from August 2017 to December 2018. Histopathology reports with malignancy were compared to their cytological diagnosis.
 Results: A total of 141 cases were included in the study. Among the study population, Bronchogenic carcinoma was found more prevalent in female. The sensitivity, specificity, positive predictive value, negative predictive value and overall accuracy of broncho-alveolar lavage in the diagnosis of lung cancer were 88.1%, 97.98%, 94.7%, 95.1% and 95.03% respectively.
 Conclusions: Brochoalveolar lavage cytology has a greater accuracy for the diagnosis of lung cancer; however, benign cases need regular follow up as there are false negative cases.
Highlights
Diseases of the lung are very common in Nepal
Diagnostic role of bronchoalveolar lavage based, procedure which allows examination of bronchial tree as far as distal lung parenchyma. It has increased the variety of specimens that can be obtained during the procedure and includes, broncho-alveolar lavage (BAL), bronchial brush, bronchial biopsy and trans-bronchial needle aspiration
Broncho-alveolar lavage is still being used as the first line of diagnostic tool for the evaluation of malignant lung lesions
Summary
Diseases of the lung are very common in Nepal. Common ones include pneumonia, tuberculosis, chronic obstructive pulmonary disease (COPD), and neoplastic conditions which includes benign and malignant tumors. Diagnostic role of bronchoalveolar lavage based, procedure which allows examination of bronchial tree as far as distal lung parenchyma. It has increased the variety of specimens that can be obtained during the procedure and includes, broncho-alveolar lavage (BAL), bronchial brush, bronchial biopsy and trans-bronchial needle aspiration. Broncho-alveolar lavage is still being used as the first line of diagnostic tool for the evaluation of malignant lung lesions It has many cytological utilities and can even guide in treatment planning without having bronchial biopsy.[3] Bronchial biopsy is still considered as the most sensitive diagnostic tool and it has highest accuracy in determining the definite histological type.[4,5] BAL has emerged as important alternative tool in obtaining a diagnosis. This study was done to correlate the cytology of broncho-alveolar lavage specimen with histopathology in malignant tumors of the lug in our setup
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
