Abstract
Aim The aim of this study was to compare the cytological features of exudative uids by conventional smear (CS) method and cell block (CB) method and also to assess the utility of the combined approach for cytodiagnosis of these effusions. Materials and Methods: One hundred cases pleural and peritoneal exudative uid samples were subjected to evaluation by both CS and CB methods over a period of 6 months between March 2019 to September 2019. Cellularity, architecture patterns, morphological features and yield for malignancy were compared, using the two methods. Along with the conventional smears, cell blocks were prepared by using 10% alcohol–formalin as xative agent. Result Cellularity and additional yield for malignancy was 5% more by the CB method. Conclusions CB produced signicantly better results while detecting malignant lesions and reducing suspicious results. CB technique denitively increased detection of malignancy in uid effusion when used as an adjunct to CSs. Also, CB provides material suitable for molecular genetic analysis for targeted therapies.
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