Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB

Novel N Chegou,Annemieke Geluk,Harriet Mayanja-Kizza,Kim Stanley,Amelia C Crampin,Gerhard Walzl,Gian Van Der Spuy,Tom H M Ottenhoff,Paul L A M Corstjens,Stephanus Malherbe,Hazel M Dockrell,Jayne S Sutherland,Martin Kidd,Marieta Van Der Vyver,Paul D Van Helden,Stefan H E Kaufmann,Andre G Loxton,Leigh A Kotzé,Ida Rosenkrands

doi:10.1136/thoraxjnl-2015-207999

Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB

Novel N Chegou, Annemieke Geluk + Show 17 more

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https://doi.org/10.1136/thoraxjnl-2015-207999

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Journal: Thorax	Publication Date: May 4, 2016
Citations: 137

Affiliation: South African Tuberculosis Vaccine Initiative, Stellenbosch University, South African Medical Research Council, Leiden University Medical Center, Makerere University, Malawi Epidemiology and Intervention Research Unit, London School of Hygiene & Tropical Medicine, MRC Unit the Gambia, University of Namibia, Max Planck Institute for Infection Biology, Statens Serum Institut

#TB Disease #Diagnosis Of TB Disease + Show 8 more

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BackgroundUser-friendly, rapid, inexpensive yet accurate TB diagnostic tools are urgently needed at points of care in resource-limited settings. We investigated host biomarkers detected in serum samples obtained from adults with...

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