Abstract
Platelet function is the result of a complex network of responses to multiple activatory and opposing inhibitory signals. Current platelet function testing conceptualises responses and activity as distinct linear pathways. Therefore, application of a single test, or even multiple arrays of platelet function tests may not readily detect platelet function aberrations. The successful clinical application of platelet function tests requires knowledge of their analytical strengths and limitations. The advent of next generation sequencing, whilst extremely useful for the characterisation of suspected inherited thrombocytopenia, currently plays a lesser role for individuals referred for the evaluation of a possible platelet function disorder.
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