Abstract
Summary A restrospective study of 16 cases of necrotizing encephalitis, in which the presence of herpes virus was definitely confirmed by culture and/or electron microscopy, demonstrated the major diagnostic value of the E.E.G. in this disease. As well as indicating the site of the primary focus, 14 out of the 16 cases showed evidence of periodic paroxystic activity with fairly typical temporal and spatial characteristics, which can establish the diagnosis when a clinical picture of acute encephalitis and a cytological reaction in the CSF are associated. Other presumptive or affirmative diagnostic criteria are discussed, and the importance of taking a biopsy is underlined. Therapeutic measures (chemotherapy and/or neurosurgery) are briefly outlined.
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