Abstract

Pericardial fluid, normally measuring 15–35 mL, is mainly an ultrafiltrate of plasma, possibly with some overflow of myocardial interstitial fluid and lymph drainage.1 Protein concentration is lower in pericardial fluid than in plasma but albumin is relatively increased, owing to its lower molecular weight and ease of transmembrane transport. Electrolyte concentrations are as predicted for a plasma filtrate, yielding fluid osmolarity consistent with such an ultrafiltrate and therefore less than plasma osmolarity.

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