Abstract
Traumatic primary brain stem injury is brain stem injury caused by mechanical head trauma. Before the development of diagnostic imaging, a pathological examination has been the nearly only diagnostic method of primary brain stem injury. Because magnetic resonance imaging (MRI) has a high resolution and CT demonstrates much artifact around the brain stem, MRI became a powerful tool for investigating primary brain stem injury. There are some types of primary brain stem injury. The author herein reviews the recent clinical studies of MRI of primary brain stem injury. The importance of early MRI examination appears to be a consensus. Our study demonstrated that small superficial lesion may be detected only a few days after injury. The acute phase within a few days after a head injury may show an unstable vital sign, thus intensive monitoring of the vital sign and manual or mechanical ventilation during a MRI examination should be employed. Direct brain stem contusion has a good prognosis compared with brain stem injury associated with diffuse axonal injury (DAI). Small superficial lesions are detected only within a few days after a head injury. Recent studies of MRI in patients with head injuries could not determine the pathology. However, the differentiation of the pathophysiology must be clinically important because the prognoses are different and distinguishable using only acute stage MRI.
Highlights
Traumatic primary brain stem injury is brainstem injury caused by mechanical head trauma
Direct brainstem contusion has a better prognosis than brainstem injury associated with diffuse axonal injury (DAI), the pathological investigation of this injury has been limited
We evaluated the magnetic resonance imaging (MRI) findings from 17 patients with primary brainstem injury in the acute stage, mostly within 2 days after injury[7]
Summary
The author reviews the recent clinical studies of MRI of primary brainstem injury. Previous pathological studies showed that most types of primary brainstem injury was accompanied with DAI and only a few patients showed direct brainstem injury without DAI[2,3]. Firsching et al examined the MRI findings of 61 consecutive patients within 7 days after severe head injury[4].
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