Abstract

Abstract Pneumocystis pneumonia (PCP), caused by the fungus Pneumocystis jirovecii (P. jirovecii), is known chiefly from its involvement of HIV patients. More recently, however, the number of PCP cases has increased after organ transplants and in other immunosuppressed patients. Laboratory diagnosis of PCP often employs traditional staining methods with low sensitivity. Molecular methods using the polymerase chain reaction can achieve a sensitivity of >95% and can – depending on the detected gene – also be used for resistance testing to trace chains of infection.

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