Abstract
Background: Obstructive jaundice is a common pathological problem that occurs when there is an obstruction to the passage of conjugated bilirubin from liver cells to intestine. Bile, a digestive fluid secreted and produce by the liver. Most common cause of obstructive jaundice is due to gallstones. Objective: The aim of our study was to evaluate the diagnostic Efficacy of MRCP and Ultrasound on obstructive jaundice. Study design: A cross-sectional prospective study was performed. Material & Method: A cross-sectional prospective study was performed in 50 patients who came with the provisional diagnosis of obstructive jaundice were referred to ultrasound for primitive diagnosis and were then shifted to MRCP for a detailed diagnosis. The data was collected from the outpatient department facility of Pakistan Kidney and Liver Institute Hospital, Lahore. After informed consent, data was collected from MRI GE 1.5 Tesla, Ultrasound Canon Xanio. Results: The results revealed that there are 50 patients of obstructive jaundice. 20 were females’ patients and 30 were males’ patients, with age raging from 20-40 years. There were 17 patients out of 50 in our study which ultrasound showed negative results that were positive on MRCP there were 28 patients that were positive on both ultrasound and MRCP. There were 3 patients that were positive on ultrasound but negative on MRCP and 2 patients that were negative on both modalities Conclusion: Our study concluded that higher ratio of males then females in our sample size, RHC was positive in all the patients with dominant cause of jaundice was stone with in biliary channel. We found that MRCP has better efficiency comparative to ultrasound to detect jaundice and its etiology i.e., 90% true positive. Keywords: Magnetic resonance cholangiopancreatography, Ultrasonography, Obstructive jaundice DOI: 10.7176/JHMN/91-03 Publication date: July 31 st 2021
Highlights
The biliary tree is a network of branching bile ducts that transport bile, a digestive fluid generated and secreted by the liver
There were 17 patients out of 50 in our study which ultrasound showed negative results that were positive on MRCP there were 28 patients that were positive on both ultrasound and MRCP
There were 3 patients that were positive on ultrasound but negative on MRCP and 2 patients that were negative on both modalities Conclusion: Our study concluded that higher ratio of males females in our sample size, RHC was positive in all the patients with dominant cause of jaundice was stone with in biliary channel
Summary
The biliary tree is a network of branching bile ducts that transport bile, a digestive fluid generated and secreted by the liver. An increase in either the conjugated or unconjugated component can cause jaundice or a rise in total bilirubin. The majority of benign causes were seen in people between the ages of 31 and 40, while malignant cases were more common in people between the ages of 51 and 70. The majority of patients, 56.66 percent, had malignant obstructive jaundice, whereas 43.33 percent had benign jaundice.[3]Cholestasis causes obstructive jaundice, which is a clinical sign. Cholestasis can be extrahepatic or intrahepatic, and it is frequently linked to biochemical abnormalities in liver function tests.[4] the most prevalent cause of distal common bile duct stricture is a peptic ulcer. MR scans clearly indicated biliary hemorrhage.[6]In our study we will compare the diagnostic efficacy of MRCP and Ultrasound so that medical practitioner will be clear that in which situation which will be the modality of choice in a patient with obstructive jaundice symptoms and how much a medical practitioner will rely on the results of MRCP and Ultrasound in some specific situations
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