Abstract

Inclusion and exclusion criteria for the diagnosis of acute transverse myelitis (ATM), as a basis for multicenter clinical trials, are proposed by a Transverse Myelitis Consortium Working Group.

Highlights

  • Inclusion and exclusion criteria for the diagnosis of acute transverse myelitis (ATM), as a basis for multicenter clinical trials, are proposed by a Transverse Myelitis Consortium Working Group

  • Identification of known etiologies can lead to specific treatments whereas idiopathic ATM, that constitutes about 16% of cases, has no established therapy

  • More than 200 cases of postvaccinal encephalomyelitis were reported in England in 1922-3, a complication of smallpox and rabies vaccination (Rivers TM, 1929)

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Summary

Introduction

Inclusion and exclusion criteria for the diagnosis of acute transverse myelitis (ATM), as a basis for multicenter clinical trials, are proposed by a Transverse Myelitis Consortium Working Group. Point prevalence of motor tics ranged from 3.2% to 9.6% (overall frequency 24.4%). Point prevalence of behavioral problems ranged from 2.6% to 11.0% (overall frequency 25.7%).

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