Abstract
Viruses that can be transmitted from mother to fetus during pregnancy are mainly rubella virus, cytomegalovirus, varicella zoster virus, parvovirus B19 and Zika virus. Congenital infections may lead to severe damage of the fetus or the newborn depending on the infectious agent and the term of pregnancy where the infection occurred. Symptomatic congenital infections more likely occur in case of maternal primary infection in the first half of pregnancy. Prenatal diagnosis mainly relies on PCR on amniotic fluid, and is usually very reliable. The aim of this article is to describe biological tools available for prenatal diagnosis, and management of congenital viral infections.
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