Abstract

Congenital hyperinsulinism (CHI) is a complex heterogeneous syndrome caused by gene mutations which lead to abnormal secretion of insulin from pancreatic β-cells. The clinical manifestations of neonatal CHI are not typical, and the brain damage is severe. Early recognition, diagnosis and reasonable management of neonatal CHI is very important, but difficult. In recent years, the research progresses of different aspects of CHI, such as molecular genetics, pathology, imaging technology, drug therapy and surgical treatment have been completely changed the clinical management of neonatal CHI. This article reviews recent research progress of the diagnosis and treatment of neonatal CHI. Key words: Persistent hyperinsulinemia hypoglycemia of infancy; Diagnosis; Therapeutics; Infant, newborn

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.