Abstract
Diagnostic and Therapeutic Advances in Epileptic Encephalopathy with Continuous Spike-Wave of Sleep
Highlights
International League Against Epilepsy (ILAE) defines Epileptic encephalopathy with continuous spike-waves during sleep (CSWS) is an electroclinical syndrome [1] characterized by epileptic seizures, neurocognitive regression and electrophysiological changes on electroencephalogram (EEG), namely electrical status epilepticus of sleep (ESES)
The Commission on Classification and Terminology of ILAE introduced the definition of CSWS [4], which is still under debate in scientific literature as well as by ILAE, because, e.g. “the use of CSWS and ESES is a cause of major diagnostic confusion and should be abandoned in its current form”
The ILAE Committee instead of two terms should propose one term, e.g. CSWS-related encephalopathy or at least change the acronym from CSWS to ECSWS (E meaning epileptic encephalopathy), in order to avoid the diagnosis of an electroclinical syndrome based on EEG findings [5]
Summary
Glob J Intellect Dev Disabil Copyright © All rights are reserved by Groppa Stanislav. The epileptic encephalopathy with continuous spike-waves during sleep (CSWS) is an electroclinical syndrome which affects children mostly between the age of 4 and 7 years old and remains a great challenge for clinicians. We present a brief overview of the recent advances in diagnostic and therapeutic issues of the epileptic encephalopathy with CSWS. The original studies presented in the PubMed and NCBI databases were inquired/consulted, research length was 45 years.
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