Abstract

The current study was designed to examine the association between breast cancer grading and levels of CA15-3 was studied in addition to the correlation between ABO blood groups and breast cancer. The study involved (140) breast cancer women, and (140) blood samples were collected from healthy women who served as control. The total patients were divided according to their ages into three groups (30-39), (40-49) and (≥50), and ABO blood groups. Moreover, the grades of breast cancer were divided into three groups, and their correlation with serum CA15-3 levels was studied. The current study shows a significant correlation between breast cancer grading and levels of serum CA15-3 antigen. The study also showed that breast cancer is elevated with age. The results demonstrated a great association between the ABO blood groups and breast cancer. Blood group type (A) recorded the highest frequency and percentage (42.14%) of patients with breast cancer. The non-A-blood type (O, B and AB) percentage was as follows (32.14%, 19.29% and 6.43%, respectively). Thus, monitoring breast cancer occurrences in women with blood group A early could be an and excellent strategy to control and facilitate the event of breast cancer. Keywords: Breast cancer, CA15-3, blood groups, breast cancer grading.

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