Abstract
BackgroundClinical and research utility of non-cardiac ultrasound (US) in chronic obstructive pulmonary disease (COPD) has been widely investigated. However, there is no systematic review assessing the clinical values of non-cardiac...
Highlights
Chronic obstructive pulmonary disease (COPD) is a progressive condition characterised by respiratory symptoms and airflow limitation resulting from airways and lung parenchyma inflammation usually caused by significant exposure to noxious particles and gases.[1]
Quadriceps Seven studies reported a significant reduction in the cross-s ectional area (CSA) of the rectus femoris (RFCSA) in patients with chronic obstructive pulmonary disease (COPD) compared with healthy subjects.[39 47,48,49,50,51,52]
While five studies reported a significant reduction of the rectus femoris thickness in patients with COPD compared with healthy subjects.[13 48 51,52,53,54]
Summary
Chronic obstructive pulmonary disease (COPD) is a progressive condition characterised by respiratory symptoms and airflow limitation resulting from airways and lung parenchyma inflammation usually caused by significant exposure to noxious particles and gases.[1]. There is no systematic review assessing the clinical values of non- cardiac US techniques in COPD. Of the 54 included studies, 30% (16/54) evaluated the changes in either limb muscles or diaphragmatic features before and after physical interventions; 67% (36/54) assessed the correlations between sonographic features and COPD severity. 14/15 and 9/13 studies reported a significant reduction in diaphragm excursion and thickness in COPD compared with healthy subjects, respectively; this was correlated significantly with the severity and prognosis of COPD. Conclusion US measurements of diaphragm excursion and thickness, as well as lower limb muscles strength, size and thickness, may provide a safe, portable and effective alternative to radiation-based techniques in diagnosis and prognosis as well as tracking improvement postintervention in patients with COPD
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