Diagnostic Accuracy of MRI in Delineation of Ultrasonographically Indeterminate Female Adnexal Lesions keeping Histopathology as Gold Standard

Abstract

Objective: This study was performed to check the diagnostic accuracy of MRI in the detection and delineationof sonologically indeterminate adnexal masses as benign or malignant, keeping histopathology as goldstandard.Study Design: Cross-sectional study.Place and Duration of Study: This cross-sectional study was conducted at the Department of Diagnosticst st Radiology of POF Hospital, Wah Cantt, Pakistan, from 1 December 2018 to 31 May 2019.Materials and Methods: All female patients (15-80 years) with sonographically diagnosed indeterminateadnexal masses, both symptomatic and incidental, were included in the study. Patients who were unfit forsurgery and those for whom MRI is contraindicated (cardiac pacemakers, intracranial metal clips,claustrophobic patients, hypersensitivity to contrast) were excluded. Total of 115 patients meeting theinclusion criterion underwent an MRI examination. All patients had undergone surgery in the concerned ward,and a histopathology report was followed. MRI findings were compared with histopathological findings. Datawas entered and analysed via SPSS version 26.Results: Mean age of the patients was 48.22±10.5. Out of 115 patients, there were 74 (64.3%) cases related tothe uterine mass category, 35 (30.4%) were related to ovarian mass category, and 6 (5.2%) fell in theExtraovarian/Extrauterine mass category. Out of 115 patients, 74 (64.3%) patients had a mass size <3cm, 35 hadthe size of 3-5 cm (5.2%), and 6 had size >5 cm (5.2%). The sensitivity of MRI was calculated to be 77.14%,specificity was 87.5%, positive predictive value was 72.9 %, and negative predictive value was 89.7 %.Conclusion: MRI has high sensitivity and specificity in diagnosing adnexal masses and therefore, can serve as agood choice in the delineation of sonographically indeterminate adnexal masses.