Abstract
Background: Recent advances in imaging technology has made it possible to diagnose abdominal masses in the early stages along with accurate image-guided localization of biopsy sites. Contrast-enhanced Computed tomography (CECT) abdomen is one such imaging tool. This study aims to establish the diagnostic accuracy of CT scans in detecting Wilm's tumour.
 Methodology: This descriptive cross-sectional study was conducted in the Department of Radiology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, from 20-10-2018 till 04-20-2019. A total of 196 patients who were clinically suspected of renal masses were included in this research project. CECT scan abdomen was acquired. The final diagnosis was based on histopathology.
 Results: Mean age in our study was 13.4±5.7 months. 104 (53.1%) were male, and 92 (46.9%) were female, respectively. Moreover, out of 196 patients, sensitivity, specificity, both the positive and negative predictive value along with diagnostic accuracy of CECT scan for diagnosis of Wilm's tumour by taking histopathology as the gold standard was found to be 93.4%, 91.8%, 95%, 89.4% and 92.8% respectively.
 Conclusion: It is concluded from the study results that the Abdominal CECT scan, despite its high radiation dose, is relevant and accurate in making a diagnosis of Wilms tumour, making it significantly helpful in early disease detection in poor resource settings such as ours where patients usually present late for treatment.
Highlights
Wilms' tumour, known as nephroblastoma, is renal cancer that typically occurs in children and rarely in adults
Increasing parents' awareness could help identify these children earlier, leading to reduced morbidity and mortality. This cross-sectional study was conducted in the Department of Radiology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, for 6 months from October 2018 till April 2019
After approval from the Institutional review board, written informed consent was obtained from the parents/guardians of the patients who were referred to the radiology department for Contrast-enhanced Computed tomography (CECT) Abdomen having suspected renal masses
Summary
Wilms' tumour, known as nephroblastoma, is renal cancer that typically occurs in children and rarely in adults. It comprises 6% of all pediatric malignancies and over 95% of all childhood kidney tumors[1]. Out of 196 patients, sensitivity, specificity, both the positive and negative predictive value along with diagnostic accuracy of CECT scan for diagnosis of Wilm's tumour by taking histopathology as the gold standard was found to be 93.4%, 91.8%, 95%, 89.4% and 92.8% respectively. Conclusion: It is concluded from the study results that the Abdominal CECT scan, despite its high radiation dose, is relevant and accurate in making a diagnosis of Wilms tumour, making it significantly helpful in early disease detection in poor resource settings such as ours where patients usually present late for treatment
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Endorsing Health Science Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
