DIAGNOSTIC ACCURACIES OF HRCT CHEST IN COMPARISON WITH RT-PCR IN DIAGNOSIS OF CORONAVIRUS DISEASE (COVID-19) IN A TERTIARY CARE HOSPITAL.

Abstract

Objective:-To compare the diagnostic accuracies of HRCTchest and RT-PCR results in diagnosis of coronavirus disease (COVID-19) in a tertiary care hospital in Kolar. Methodology This was a prospective study approved by Ethical Review Committee of R L JALAPPA Hospital. From Dec 2021 to May 2022, a total of 48 CT chest were performed in this hospital. Patients aged above 18 years, irrespective of gender, who were clinically suspected of COVID-19 with at least one RT-PCR test and HRCT chest done, individuals with close contact history and admitted patients were included. Patients with interval of more than seven days between HRCT chest acquisition and rst PCR sampling, patients with pulmonary and extra pulmonary lung malignancy, chest trauma, previous chest surgery were excluded. For those patients with negative rst PCR but suspicious clinical symptoms suggesting COVID-19, a second PCR was conducted within 3 days after the rst, the result of which was taken as diagnostic gold standard. For patients with only a single RT-PCR test, the test result was taken as the diagnostic gold standard Results:- Sensitivity of HRCTin diagnosing Covid 19 was 86.49%, Specicity of HRCT in diagnosing Covid 19 was 27.27%, Positive Predictive Value of HRCT in diagnosing Covid 19 was 80.00%, Negative Predictive Value of HRCT in diagnosing Covid 19 was 37.50% and Accuracy of HRCT in diagnosing Covid 19 was 72.92%