Abstract

It has been demonstrated that a number of genes are abnormally expressed in ulcerative colitis (UC) patients. In particular, the FAM5C (Family with Sequence Similarity 5, member C) gene is significantly under-expressed in patients with UC compared to healthy controls. Accordingly, the level of FAM5C can be used to diagnose and/or prognose UC in an individual. A new method for diagnosing and/or prognosing UC using biomarkers for UC, including FAM5C, is also disclosed.

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