Abstract

Peritoneal tuberculosis (PTB) is an uncommon extrapulmonary infection mimickng primary peritoneal cancer (PPC). We retrospectively included 23 women with PTB and 47 women with PPC treated in a medical center to study the clinical and radiological features that differentiate PTB from PPC. Body temperature above 38 °C was a unique feature of PTB (34.7% versus 0%, p < 0.001). Body Mass Index (BMI) was lower (21.9 ± 3.7 versus 25.2 ± 4.1, p = 0.003), white blood cell (WBC) count was lower (5179.6 ± 1502.2 versus 7716.2 ± 2741.8, p < 0.001), and CA-125 level was lower (508.0 ± 266.1 versus 2130.1 ± 2367.2 U/mL, p < 0.001) in PTB compared with PPC. Imaging detected more pulmonary infiltration and consolidation (52.2% versus 6.4%, p < 0.001), and less omental/mesentery changes (52% versus 83%, p < 0.001) in PTB compared with PPC. The operated patients received earlier treatment compared to patients without operation (7.9 ± 5.3 days versus 17.2 ± 11.0 days, p = 0.010). In conclusion, fever above 38 °C, lower BMI, lower WBC count, less elevated CA-125 level, and imaging of less omental involvement were features of PTB differentiated from PPC.

Highlights

  • Tuberculosis (TB) is an important global health problem

  • The patients of Peritoneal tuberculosis (PTB) were in a wide range of age, but the mean age was similar between the two groups of patients

  • Our study shows that the duration from initial admission to anti-tuberculosis treatment after confirmation of PTB is much longer in patients without operation than patients receiving operation

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Summary

Introduction

Tuberculosis (TB) is an important global health problem. According to the WorldHealth Organization, it was one of the top 10 causes of death worldwide in 2018 and is the leading cause of death of people with human immunodeficiency virus (HIV) [1]. Tuberculosis (TB) is an important global health problem. Health Organization, it was one of the top 10 causes of death worldwide in 2018 and is the leading cause of death of people with human immunodeficiency virus (HIV) [1]. An estimated 1.3 million people died from TB each year and an estimated 10.0 million people newly sick with TB in 2018 [2]. More than half of TB were diagnosed in developing countries, including India, Indonesia, China, the Philippines, and Pakistan [2]. In Taiwan, TB is decreasing year by year. There were 9759 new cases and 511 TB-related deaths in

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