Abstract

s / Osteoarthritis and Cartilage 20 (2012) S54–S296 S269 No significant interactions were found between race or gender and radiographic knee, hip, or hand OA with lumbar spine IRF. Conclusion: Interestingly, the strongest associations were found between OA of the facet joints of the spine, which are synovial joints, and OA of both the knees andhands, also synovial joints. Thesefindings also suggest that hip OA may have a different etiology from that of lumbar spine IRF; this is not surprising given the prevalence of morphometric abnormalities cited as a common etiology for hip OA. The fact that lumbar OST, but not DSN, were associatedwith kneeOAmay inpart bedue to relianceonK-L grade, a system weighted for the presence of osteophyte, for defining OA of the knee. Nevertheless, these findings underscore the importance of analyzing lumbar spine IRF as separate outcomes for OA studies as they likely reflect different processes ongoing in the joint organ during the course of this disease. Table. Adjusted associations between lumbar spine IRF and radiographic knee, hip and hand OA DSN OR(95% CI) OST OR(95% CI) FOA OR(95% CI) Knee OA 1.16 (0.84, 1.59) 1.62 (1.16, 2.27) 1.69 (1.15, 2.49) Hip OA 0.99 (0.71, 1.38) 1.01 (0.72, 1.43) 0.89 (0.60, 1.31) Hand OA 1.14 (0.79, 1.63) 0.81 (0.55, 1.18) 1.82 (1.15, 2.89) 532 DIAGNOSIS OF LUMBAR SPINAL STENOSIS: AN UPDATED SYSTEMATIC REVIEW E. de Schepper , G. Overdevest , P. Suri , W. Peul , E. Oei , B. Koes , S. Bierma-Zeinstra , P. Luijsterburg . 1 Erasmus MC, Rotterdam, Netherlands; 2 Leiden Univ. Med. Ctr., Leiden, Netherlands; Harvard Med. Sch., Boston,

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