Diagnosis of Hemochromatosis

Abstract

Letters17 August 1999Diagnosis of HemochromatosisLawrie W. Powell, MD, PhD, D. Keith George, MBChB, MRCP, and Sharon McDonnell, MDLawrie W. Powell, MD, PhDThe Queensland Institute of Medical Research; Brisbane, Australia (Powell)The Queensland Institute of Medical Research; Brisbane, Australia (George)Centers for Disease Control and Prevention; Atlanta, GA 30333 (McDonnell)Search for more papers by this author, D. Keith George, MBChB, MRCPThe Queensland Institute of Medical Research; Brisbane, Australia (Powell)The Queensland Institute of Medical Research; Brisbane, Australia (George)Centers for Disease Control and Prevention; Atlanta, GA 30333 (McDonnell)Search for more papers by this author, and Sharon McDonnell, MDThe Queensland Institute of Medical Research; Brisbane, Australia (Powell)The Queensland Institute of Medical Research; Brisbane, Australia (George)Centers for Disease Control and Prevention; Atlanta, GA 30333 (McDonnell)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-4-199908170-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Our discussion of the laboratory criteria for hemochromatosis was clearly in the context of an otherwise healthy person or one with clinical features suggestive of the disease. We stated that in this situation “the serum ferritin level defines the point at which hemochromatosis is expressing iron overload and treatment should be initiated.” It is then that the serum ferritin level exquisitely reflects body iron stores. Other conditions can indeed cause an elevation in serum ferritin level out of proportion to iron stores, and we listed inflammation, infection, and cancer because they can complicate hemochromatosis. Renal disease is rare ... Author, Article, and Disclosure InformationAffiliations: The Queensland Institute of Medical Research; Brisbane, Australia (Powell)The Queensland Institute of Medical Research; Brisbane, Australia (George)Centers for Disease Control and Prevention; Atlanta, GA 30333 (McDonnell) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoDiagnosis of Hemochromatosis Lawrie W. Powell , D. Keith George , Sharon M. McDonnell , and Kris V. Kowdley Diagnosis of Hemochromatosis Lawrie W. Powell , D. Keith George , Sharon M. McDonnell , and Kris V. Kowdley Diagnosis of Hemochromatosis Kamyar Kalantar-Zadeh and Friedrich C. Luft Metrics 17 August 1999Volume 131, Issue 4Page: 311-312KeywordsAttentionBone marrowHemochromatosisInflammationRenal diseasesRenal failureResearch laboratoriesSerum ferritin levels Issue Published: 17 August 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...