Abstract
Abstract: We are reporting a case of acute osteomyelitis in previously irradiated bone. In nonirradiated bone the diagnosis of acute osteomyelitis is established by the mismatch between focal indium-111 whole body scintigraphy (WBC) bone uptake and bone marrow replacement as seen on the Tc-99m sulfur colloid scans in areas of acute osteomyelitis. In previously irradiated bone, the bone marrow is absent due to radiation effects. Accordingly, the combination of indium-111 WBC and Tc-99m sulfur colloid mismatch cannot be implemented. In this case, we found that in spite of previous irradiation of the bone there is uptake in the bone matrix due to cortical and osteoblastic activity as seen on the Tc-99m MDP bone scan. For this reason we are recommending that for the diagnosis of acute osteomyelitis in previously irradiated bone, dual isotope imaging using indium-111 WBCs and Tc-99m MDP is more accurate than indium-111 WBCs and Tc-99m sulfur colloid.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
