Abstract
Introduction: Post-transplant lymphoproliferations (PTL) are a severe complication of solid organ transplants. Their locations can be extra-nodal. Observation: The diagnosis and management of a non-Hodgkin's plasmablastic lymphoma of mandibular localization affecting a 66-year-old kidney transplanted patient are reported here. Comment: The main risk factors for non-Hodgkin lymphoma are immunosuppression and infection with Epstein-Barr virus. Clinical and radiographic examinations, which are not specific, must be supplemented by a histological examination. Treatment which is not consensual will most often consist of a reduction in immunosuppression coupled with chemotherapy. Conclusion: Despite a constant evolution in the incidence and clinical picture of post-transplant lymphomas, the role of the dentist remains essential in the early detection of lesions.
Highlights
According to the new classification from the World Health Organization, post-transplantation lymphoproliferative (PTL) syndromes cover a heterogeneous set of benign or malignant pathologies, including lymphoma, occurring in a context of post-transplantation immunosuppression due to quantitative or qualitative T lymphocyte damage [1]. They represent a severe complication occurring in patients with solid organ transplants such as kidneys
Since 2011, only one case of oral cavity plasmablastic lymphoma occurring after solid organ transplantation has been documented
Despite a constant change in the incidence and clinical picture of PTL, as well as an improvement in their management, these blood disorders still represent a serious complication of transplants
Summary
Diagnosis of a plasmoblastic lymphoma of the mandible after renal transplantation: a case report. Abstract -- Introduction: Post-transplant lymphoproliferations (PTL) are a severe complication of solid organ transplants. Observation: The diagnosis and management of a non-Hodgkin’s plasmablastic lymphoma of mandibular localization affecting a 66-year-old kidney transplanted patient are reported here. Comment: The main risk factors for non-Hodgkin lymphoma are immunosuppression and infection with Epstein-Barr virus. Treatment which is not consensual will most often consist of a reduction in immunosuppression coupled with chemotherapy. Conclusion: Despite a constant evolution in the incidence and clinical picture of post-transplant lymphomas, the role of the dentist remains essential in the early detection of lesions
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