Abstract
Small Intestinal Bacterial Overgrowth (SIBO) is a clinical condition, in which excess amounts of bacteria are found in small intestine. SIBO occurred when normal homeostatic mechanism which control enteric bacteria population disrupted. Elderly patients are more vulnerable to SIBO which can be caused by two conditions, which are gastric acid reduction and disproportionately drugs consumption which then caused hypomotility. There are several methods to diagnose SIBO, but diagnose often begin with suspicion and history of risk factors of SIBO. There are two most frequent tests in SIBO diagnostic, which are bacterial culture examination and breath test. Treatments of SIBO are: (1) Treatment of underlying disease and improvement of medical condition; (2) Eradication of excess bacterial growth; (3) Resolve nutritional deficiencies which related to SIBO.
Highlights
Small intestinal bacterial overgrowth (SIBO) is a clinical condition, in which excess amount of bacteria are found in small intestine.[1]
Pathogenesis of this disease VWLOOQRWIXOO\XQGHUVWRRG\HW$W¿UVWWKLVGLVHDVHRQO\ occurred in small numbers of patients, it was estimated to occurred in more patients
SMALL INTESTINAL BACTERIAL OVERGROWTH (SIBO) is a clinical condition which caused by abnormal numbers of bacteria in small intestine, with different predisposing factors, like motility disorders and disruption in gastric acid barrier.[7]
Summary
**Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine University of Indonesia/Dr Cipto Mangunkusumo General National Hospital, Jakarta. IRXQGLQVPDOOLQWHVWLQH6,%2RFFXUUHGZKHQQRUPDOKRPHRVWDWLFPHFKDQLVPZKLFKFRQWUROHQWHULFEDFWHULD SRSXODWLRQGLVUXSWHG(OGHUO\SDWLHQWVDUHPRUHYXOQHUDEOHWR6,%2ZKLFKFDQEHFDXVHGE\WZRFRQGLWLRQV which are gastric acid reduction and disproportionately drugs consumption which caused hypomotility. ABSTRAK 6PDOO LQWHVWLQDO EDFWHULDO RYHUJURZWK 6,%2 DWDX SHUWXPEXKDQ EDNWHUL EHUOHELKDQ GL XVXV KDOXV DGDODK. VXDWXNRQGLVLNOLQLNGLPDQDWHUGDSDWEDNWHULGDODPMXPODK\DQJEHUOHELKDQGLXVXVKDOXV6,%2WHUMDGLNHWLND mekanisme homeostatis normal yang mengontrol populasi bakteri enterik terganggu. Pasien berusia lanjut OHELKUHQWDQPHQJDODPL6,%2\DQJGDSDWGLVHEDENDQROHKGXDNHDGDDQ\DLWXSHQJXUDQJDQDVDPODPEXQJ dan konsumsi obat-obat secara tidak proporsional yang kemudian menyebabkan hipomotilitas. Ada beberapa FDUDXQWXNPHQHJDNNDQGLDJQRVLV6,%2QDPXQGLDJQRVLVVHULQJGLPXODLGHQJDQNHFXULJDDQGDQULZD\DWIDNWRU ULVLNR6,%27HUGDSDWGXDPDFDPSHPHULNVDDQ\DQJSDOLQJVHULQJGLODNXNDQGDODPSHQHJDNDQGLDJQRVLV6,%2 \DLWXSHPHULNVDDQNXOWXUEDNWHULGDQEUHDWKWHVW7DWDODNVDQD6,%2DQDWDUDODLQ 3HQJREDWDQSHQ\DNLWGDVDU GDQ SHUEDLNDQ NRQGLVL HUDGLNDVL SHUWXPEXKDQ EDNWHUL \DQJ EHUOHELKDQ PHQJDWDVL GH¿VLHQVL QXWULVL \DQJEHUNDLWDQGHQJDQ6,%2
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