Abstract
Bone disease is a well-recognized consequence of chronic renal failure. Its development during the critical years of skeletal growth commonly results in bone deformities and growth retardation in pediatric patients with advanced renal disease. Although the association of bone disease and renal failure has been described more than a century ago, the management of renal osteodystrophy continues to be a major challenge for pediatric nephrologists because of the severity of its clinical sequelae. Moreover, the improvement in long-term outcome of maintenance dialysis and successful renal transplantation make the prevention, early diagnosis and prompt treatment of renal bone disease essential if these devastating complications of bone disease are to be avoided.
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