Abstract
Lymphomatoid papulosis (LyP), a low-grade malignant T-cell lymphoma, belongs to the spectrum of cutaneous CD30+ lymphoproliferative diseases. It clinically manifests as necrotic papules or nodules, and superficial scar may be left after regression in some cases. Since lesions tend to recur and heal spontaneously, the lesions at different stages of evolution usually coexist. The histologic manifestations of LyP are various, and usually present as a spectrum. Pathologically, LyP is characterized by the presence of CD30 + neoplastic cells, and can easily be mistaken for other benign or malignant diseases. At present, no specific treatments for LyP are available, and no treatments can alter the natural history of LyP. In general, active treatments are not recommended. LyP has a good prognosis, but may be followed by other malignant lymphomas, so a long-term follow-up is warranted. Key words: Lymphomatoid papulosis; Lymphoma, T-Cell; Diagnosis; Pathology, clinical; Immunophenotyping
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