Diagnosis and Treatment of Juvenile Nasopharyngeal Angiofibroma: Impressions from a University Hospital

Abstract

Objective: Describe the characteristics of diagnosis and treatment of JNA at a teaching hospital. Method: A retrospective cross-sectional study was conducted by revision of medical records from patients treated for juvenile nasopharyngeal angiofibroma between January 2007 and October 2010. Results: There were 11 patients, all males, with mean age of 15.18 years, who underwent surgery. Nasal obstruction was the initial symptom (54.55%), followed by epistaxis (45.45%). Stage II of Andrews was most commonly observed (54.55%). Preoperative embolization was performed in 45.45% of patients, and the most common approach was endoscopic-assisted mid-facial degloving (72.73%). Intraoperative blood transfusion was necessary in 72.73%, due to decrease in hemoglobin average from 13.18 to 8.54 g/dL. ICU hospitalization average was 2.78 days, and hospital discharge average was 8.18 days. Recurrence occurred in 2 cases, totaling 18.18% of failure. Preoperative embolization and use of endoscope reduced risk of relapser=0.77 (Pearson correlation). Conclusion: We described our experience and found that preoperative embolization and use of endoscope reduced risk of relapse.