Diagnosis and treatment of gastritis cystica profunda

Abstract

Objective To investigate the diagnosis and treatment of gastritis cystica profunda. Methods The clinical data of 7 patients with GCP were retrospectively analyzed. The clinical manifestations, auxiliary examination results, treatment and pathological characteristics were analyzed. Results All of the 7 patients had no history of gastric surgery or family history of related diseases. No obvious abnormality was observed in laboratory examination. There were 4 cases of abdominal pain, 2 cases of abdominal distension, 1 case of choking, 2 cases of insufficiency, 1 case of nausea and vomiting. Six patients with endoscopic ultrasonography showed single uplift and inhomogeneous echo in some parts. The lesion was located in 4 cases of gastric antrum, 2 cases in the stomach and 1 case in the bottom of the stomach. Five patients with enhanced CT scan showed no obvious enhancement in the arterial phase of the disease, and the inhomogeneous enhancement of the venous phase. One case indicated thickening of the stomach wall, and 4 cases showed nodular protrusion to the stomach cavity. Among the 7 patients, 3 cases underwent local excision of surgery, 3 cases underwent endoscopic submucosa dissection (ESD) and 1 case infiltrated endoscopic mucosal resection (EMR). In the postoperative pathology, 1 case combined with low-grade intraepithelial neoplasia, 1 case with ectopic pancreas, 1 case with the involvement of muscularis propria. Conclusions The clinical manifestations of GCP are nonspecific, CT combined with endoscopic ultrasonography can provide reference for the diagnosis, evaluation of therapeutic lesions smaller without breaking the submucosa is feasible under endoscopy before operation, surgical treatment is performed for patients who are involved in the myometrium and the following or malignant components. Key words: Gastritis cystica profunda; Clinical features; Diagnosis; Treatment