Abstract

SUMMARY The treatment of follicular lymphoma (FL) has advanced in the past decade. The routine use of monoclonal antibodies, arrival of bendamustine and application of radioimmunotherapy have ushered in major improvement in response rates for patients with indolent lymphoma. Studies have documented an improvement in progression-free survival and overall survival with chemoimmunotherapy followed by maintenance rituximab. The purpose of this review is to share an overview of recent advances in clinical care and research underway that will be incorporated into clinical practice in the foreseeable future. We will restrict our review to FL because the wide variety of types of indolent lymphoma makes it impossible to cover all of them in a brief review. FL is the most common indolent lymphoma and the general approach to diagnosis and treatment of this disease is often utilized as a foundation for the diagnosis and treatment of indolent lymphomas in general.

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