Abstract

Alzheimer’s Disease (AD) exerts a significant worldwide impact. An estimated 44 million individuals currently live with this Major Neurocognitive Disorder. There are about 6.2 million Americans with AD dementia today and AD kills more people than breast cancer and prostate cancer combined. The National Institute on Aging estimates that the prevalence of AD doubles every five years beyond the age of 65 and as the population ages, a greater proportion of the population is affected. AD will cost the United States over $355 billion in 2021, rising to over $1.5 trillion by 20501 imposing a significant economic burden. Early diagnosis and treatment of neurocognitive disorders are critical in determining treatment approaches and shaping policy to prepare for the deluge of cases to come. This review describes current diagnostic approaches and treatment advances for AD.

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