Diagnosis and treatment of adrenal teratoma: a report of 5 cases and review of literature

Abstract

Objective To discuss the feature, diagnosis and treatment, and proguosis of adrenal teratoma. Methods Clinical data of 5 patients with confirmed adrenal teratoma were retrospectively reviewed.There were 2 males and 3 females, with a median age of 57 years (35-64). The mean tumor size was 5-8.5 cm.The tumors were located on the right side in 3 cases and the left side in 2.Two cases were detected by routine health check up, and 2 were detected with the complains of fatigue and 1 with complains of back pain.All cases had normal value of endocrinology and biochemistry tests.Ultrasound examination showed cystic tumor on adrenal gland with uneven echo.CT showed irregular, inhomogeneous adrenal neoplasms in adrenal gland.The tumor presented as inhomogenous high signal intensity on MRI T1 and T2. Results Five patients underwent laparoscopic adrenalectomy, and histopathology showed adrenal mature teratoma.No recurrence occurred after operation in all patients. Conclusions These cases combined with literature review indicate that adrenal teratoma is extremely rare which has no characteristic clinical manifestations; and laparoscopic adrenalectomy is a feasible, effective technique with excellent results. Key words: Adrenal gland neoplasms; Teratoma; Laparoscopes