Abstract
Objective To evaluate the methods used for diagnosis and surgical treatment of insulinoma. Methods A total of 49 cases of insulinoma treated in our hospital in the past 20 years were reviewed. Results Of the 49 cases, 45 had typical Whipple's triad. The sensitivity of the disease was 47.3% (18/38) to ultrasonography, 60% (15/25) to CT, 64.7% (11/17) to MRI, 83.3% (5/6) to selective arteriography, 97.8% (44/45) to intraoperative palpation and 100% to intraoperative ultrasonography (12/12). Surgical enuleation was performed in 31 cases, resection of pancreatic tail in 4, resection of pancreatic body and tail in 7, Whipple in 1 and PPPD in 1. Conclusions Whipple's triad and IRI/G0.3 can be used as parameters to diagnose insulinoma. Perioperative accurate localization of the tumors is difficult. Intraoperative ultrasonography and palpation is the best method for localizing diagnosis of the tumor. Enucleation is the best choice for treatment of benign insulinoma and can result in the lowest occurring rate of complications.
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