Abstract
Systemic lupus erythematosus (SLE) is a heterogenous autoimmune disorder with a complex pathogenesis that results in interactions between susceptibility genes and environmental factors. Almost 90 percent of SLE cases are in women; especially in child bearing age. It is a chronic inammatory disease with multisystemic involvement in which immune complex deposition causes damage to the tissues involved. Maternal and fetal mortality and morbidity are still signicantly high despite improvements in outcomes. Maternal morbidity includes higher risk of disease ares, preeclampsia and other pregnancy-related complications. Fetal issues include higher rates of preterm birth, fetal growth restriction, and neonatal lupus syndromes. Management option is limited to few safer drugs. A multidisciplinary approach, with close medical, obstetric and neonatal monitoring, is essential for optimal outcomes. This case report describes a 27 years old primigravida diagnosed with SLE for the rst time in pregnancy, evaluated and managed with a good fetomaternal outcome.
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