Abstract
During the last decade repeated studies have documented the existence of a poor neonatal adaptation syndrome in some newborns exposed to these drugs during pregnancy.1 While the syndrome includes features seen in neonatatal withdrawal of other psychotropic drugs (such as opioids, benzodiazepines, barbiturates, and alcohol), in the case of SSRIs and SNRIs the presentation is also characterized by respiratory distress, sometimes necessitating ventilatory support1 (Table 1). While the etiology of the poor adaptation syndrome is still debated, several findings may shed light on its pathophysiology:
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