Diagnosis and Management of Cryptogenic Multifocal Ulcerative Stenotic Enteritis with Nephrotic Syndrome: A Systematic Review

Abstract

Chronic or recurring subileus condition arising from several tiny intestinal fibrous strictures and several shallow ulcers of the small intestines characterizes cryptogenic multifocal ulcerative stenotic enteritis, an exceedingly uncommon disorder characterized by chronic or relapsing enteritis (asymptomatic at times). It is uncertain as the cause and the pathology is not fully understood. Glucocorticosteroids are recommended for long-term therapy. However, most individuals end up becoming dependent on corticosteroids by increasing the ability to conduct accurate diagnostic work and the capacity to do an endoscopic therapy for an obstruction, deep enteroscopy may eliminate the necessity for surgery and save patients excessive small bowel resections. Whether the onset of cryptogenic multifocal ulcerative stenotic enteritis in this patient is related to thrombotic microangiopathy is still unclear and it is more likely to consider secondary changes in this disease. Although it’s an uncommon disorder, we recommend that cryptogenic multifocal ulcerative stenotic enteritis (chronic or relapsing subileus episodes resulting from numerous small intestinal strictures) should be taken into consideration when chronic or recurrent subileus episodes develop from several shallow ulcers of the small intestines. Endoscopic therapy of stenosis, if effective, can avoid surgery and unnecessary small bowel resections.