Abstract
Acanthamoeba keratitis (AK) is a vision-threatening corneal infection that most frequently affects contact lens wearers. Severe pain out of proportion to the corneal findings, radial keratoneuritis, and ring infiltration are relatively specific clinical manifestations of AK. The diagnosis of AK is challenging and it is often misdiagnosed because of atypical presentations. The definitive diagnosis of AK requires the presence of Acanthamoeba cysts or trophozoites in corneal lesions, and a high index of clinical suspicion is important for early diagnosis. In this review, we describe the clinical manifestations, including atypical findings, and management of AK.
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