Abstract
Background: Cervical dysplasia is the most common gynecological disorder of modern era. It initiates around the squamocolumnar junction of the cervix commonly due to the infection of human papilloma virus. Large loop excision of transitional zone is globally a standard procedure of choice both for diagnosing and treating cervical dysplasia. Pap smear is a fast and easy assessment tool for detecting cervical lesions, but it is relatively unreliable.
 Methodology: Fifty patients of age group 35 to 65 years patients having normal looking cervix with abnormal pap smear or suspicious looking cervix with or without abnormal pap smear, were selected for the study after informed consent. The procedure for LLTEZ was performed under strict aseptic measures in the procedural room and the biopsy specimen was sent for histopathological examination. The pathological findings were presented as percentages.
 Results: 66% cervical biopsy specimens were suggestive of chronic cervicitis and 24% samples were suggestive of chronic cervicitis with squamous metaplasia. Mild dysplasia in 4% samples, moderate and severe dysplasia were seen in 2% samples.
 Conclusion: LLETZ is an efficient procedure to deal with cervical dysplasia. It must be recommended for the work-up of uncertain gynecological presentations. The expertise of professionals must be improved through training to obtain maximum benefits.
Highlights
Cervical dysplasia, which is the abnormal growth of epithelial tissue around the squamocolumnar junction of cervix ranges from cervical intraepithelial neoplasm (CIN) stage I to stage III
66% cervical biopsy specimens were suggestive of chronic cervicitis and 24% samples were suggestive of chronic cervicitis with squamous metaplasia
As the cervix is directly exposed to human papilloma virus (HPV), this is the most vulnerable site for dysplasia and carcinoma at a younger age
Summary
Cervical dysplasia, which is the abnormal growth of epithelial tissue around the squamocolumnar junction (transformation zone) of cervix ranges from cervical intraepithelial neoplasm (CIN) stage I (mild) to stage III (severe). It evolves throughout the life span of a sexually active women. [5,3] Large loop excision of transformation zone (LLETZ) is the current gold standard treatment for all the patients with CIN It is a dependable, inexpensive and minor surgical procedure, routinely used in outpatient department for diagnosis as well as treatment of the cervical lesions. Mitchell et al concluded that inadequate sampling and errors make the pap smear conclusion doubtful whether it is negative or positive for cytology the practice of relying on cytology should be discouraged and must be followed by histopathology through cervical biopsy. [9] Present study is conducted to observe its practicability, fruitfulness of the procedure and to find out the frequency of the cervical lesions in biopsy samples according to histopathological findings
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