Abstract

Predicting the presence of Microaneurysms in the fundus images and the identification of diabetic retinopathy in early-stage has always been a major challenge for decades. Diabetic Retinopathy (DR) is affected by prolonged high blood glucose level which leads to microvascular complications and irreversible vision loss. Microaneurysms formation and macular edema in the retinal is the initial sign of DR and diagnosis at the right time can reduce the risk of non proliferated diabetic retinopathy. The rapid improvement of deep learning makes it gradually become an efficient technique to provide an interesting solution for medical image analysis problems. The proposed system analysis the presence of microaneurysm in fundus image using convolutional neural network algorithms that embeds deep learning as a core component accelerated with GPU(Graphics Processing Unit) which will perform medical image detection and segmentation with high-performance and low-latency inference. The semantic segmentation algorithm is utilized to classify the fundus picture as normal or infected. Semantic segmentation divides the image pixels based on their common semantic to identify the feature of microaneurysm. This provides an automated system that will assist ophthalmologists to grade the fundus images as early NPDR, moderate NPDR, and severe NPDR. The Prognosis of Microaneurysm and early diagnosis system for non - proliferative diabetic retinopathy system has been proposed that is capable to train effectively a deep convolution neural network for semantic segmentation of fundus images which can increase the efficiency and accuracy of NPDR (non proliferated diabetic retinopathy) prediction.

Highlights

  • The main causing of visual loss in the world is diabetic retinopathy

  • The results show that the pathological lesions and normal retinal structures are statistically different based on Amplitude modulation-frequency -modulation (AM-FM) characteristics

  • The resulting image is separated into smaller parts, called patch as shown in Figure 6(c), once the optical disk has been removed from the original image. 32 × 32 pixel patch size is set exudates patch classification as shown in figure 6(d)

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Summary

INTRODUCTION

The main causing of visual loss in the world is diabetic retinopathy. In the initial stages of this disease, the retinal microvasculature is affected by several abnormalities in the eye fundus such as the microaneurysms and/or dot hemorrhages, vascular hyper permeability signs, exudates, and capillary closures [1]. Detection and treatment of DR are very important because it is a progressive disease and its severity depends on the number and types of lesions in the fundus image The main components of a healthy retina are blood vessels, optic discs, and macula, and any variations in these components are symptoms of eye disease. NPDR, referred to as the Diabetic Retinopathy background occurs when the blood vessels inside of the retina are weakened by diabetes, causing blood leakage and fluid on the retinal surface [6]. VOLUME 8, 2020 retinopathy (PMNPDR) utilizing a deep convolutional neural network for semantic segmentation of fundus images which can increase the efficiency and accuracy of NPDR.

LITERATURE REVIEW
EXPERIMENTAL RESULTS AND DISCUSSION
RELATIVE SPECIFICITY AND SENSITIVITY RATIO
CONCLUSION
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