Abstract
Objective: To determine the association between the acute inflammatory markers and Diabetic Renal-Retinal Syndrome in our patients. Methods: A total of 44 patients were included in this transverse (cross sectional), observational, analytical, and comparative study. Two groups of patients were created. Results: In patients with chronic renal failure, stages 3, 4, or 5 (scale 1 to 5) were identified and divided into two groups: Group I (Patients with concomitant diabetic retinopathy stabilized with photocoagulation) 22 patients. Group II (Patients with progression of retinopathy, after photocoagulation, in the form of intraocular bleeding) 22 patients. The number of patients with chronic renal failure in stage 3 was: Group I; 16. In Group II; 12 patients (OR: 1.0). Stage 4: Group I; 4 patients. Group II: 3 patients (OR: 1.0, CI 95%; 0.3843 - 2.021). Stage 5: Group I; 2 patients. Group II; 7 patients (OR: 1.8148, CI 95%; 1.0448 - 3.1523; Chi-squared (x2) 2.7450, p = 0.097). t-Test found statistical significance in Erythrocyte Sedimentation Rate (ESR): p
Highlights
When we check our reports, we realized that anemia was related to intraocular bleeding; we found that around 90% of the patients with intraocular bleeding finished in intraocular surgery, underwent in our medical unit, have diabetic chronic kidney disease
The Dialysis Outcomes and Practice Patterns Study (DOPPS) conducted in different countries, have shown that life expectancy has improved in patients with end-stage nephropathy [21] [22]
This line of research started when we wondered: why some patients with diabetic retinopathy are stabilized with photocoagulation and others not? In our first research, we found the anemia as a factor related to the progression of diabetic retinopathy after photocoagulation [23], more than glycemia or others metabolic factors
Summary
This transverse (cross sectional), observational, analytical, and comparative study was conducted from March 2011 to September 2013. Patients which were unaware of having kidney disease were detected if they have a glomerular filtration rate from 0 and 89 ml/min, based on CKD-EPI creatinine equation [19] were included. Thanks to our first study, we found that anemia was the main parameter that made the difference between patients with diabetic retinopathy who remained stables after photocoagulation versus patients with progression of the pathology, even after the photocoagulation. In this previous study, we did not much importance to the diabetic chronic kidney disease. We did not choose the type of non parametric study with any of the variables
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