Abstract
Diabetic renal disease.
Highlights
Diabetic nephropathy is associated with typical histological features
Whilst an elevation in the urinary albumin excretion rate is often the earliest sign of Diabetic nephropathy (DN), measurement of glomerular filtration is increasingly important as the disease progresses
The reporting of estimated GFR (eGFR) was designed to identify those with modest degrees of renal impairment that may have been missed by clinicians relying on serum creatinine alone
Summary
Diabetic nephropathy is associated with typical histological features. The Renal Pathology Society has proposed a histopathological classification of diabetic nephropathy [7]. The diagnosis of diabetic renal disease, usually relies on measuring the urinary albumin excretion rate and the glomerular filtration rate (GFR) and on exclusion of other causes of renal disease. Whilst an elevation in the urinary albumin excretion rate is often the earliest sign of DN, measurement of glomerular filtration is increasingly important as the disease progresses.
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